Pharmacognosy

DEPARTMENT OF PHARMACOGNOSY AND BOTANY

MPM containing cardiac glycosides

 

MPM name

Source

Constituents

Action, use

Folia Digitalis

Digitalis purpurea Linne (digitalis, foxglove),

Scrophulariaceae

purpureaglycoside A (secondary glycoside digitoxin derived by hydrolysis of one glucose residue), purpureaglycoside B, glucogitalotoxin, digitoxin, gitoxin, and gitaloxin, glucodigitoxigenin-bis-digitoxiside, glucogitaloxigenin-bis-digitoxiside, glucolanadoxin, glucoverodoxin, verodoxin; steroidal saponins (digitonin, tigonin); aromatic acids; flavonoids

heart failure insufficiency in the case of blood circulation disorders

Folia Digitalis lanatae

Digitalis lanata Ehrhart (Grecian foxglove), Scrophulariaceae

digoxin; primary glycosides are designated lanatosides A through E, digitoxigenin, gitoxigenin, gitaloxigenin digoxigenin, diginatigenin; flavonoids; steroidal saponins

cardiac insufficiency

Herba Convallaria, Folia Convallaria, Flores Convallaria

Convallaria majalis Linne (convallaria, lily-of-the-valley), C. Keiskei Miq., C. Transcaucasica Utkin ex grossh., Convallariaceae

convallatoxin, a monoglycoside composed of the genin of K-strophanthin (stropnanthidin) and the sugar of G-strophanthin (rhamnose), convallatoxol and convalloside; steroidal saponins; flavonoids, coumarins

cardiotonic;

total flavonoid content causes cholagogue action

Herba Adonidis vernalis

Adonis vernalis Linne (adonis, pheasant's eye), Ranunculaceae).

adonitoxin, cymarin, and K-strophanthin; saponins; coumarins; flavonoids

cardiotonic;

sedative

Semina Strophanthi

Strophanthus kombe Oliver,

S. hispidus DeCandolle, S. Gratus (Hook) Franch

(strophanthus), Apocynaceae

K-stophanthoside, also known as stroposide, (composed of the genin, strophanthidin, coupled to a trisaccharide consisting of cymarose, b -glucose, and a-glucose); quabain, also known as G-strophanthin (glycoside of quabagenin and rhamnose); strophantidol; cymarol. Fixed oil; saponins; ferments

Strophanthin K and G are the drugs of the aid in acute heart attack

Herba Erysimi canescentis recens

Erysimum canescens Roth. (E. diffusum Ehrh.), Brassicaceae

erysimine, erysimoside, glucoerysimoside (their aglycone is strophanthidin); fixed oils; flavonoids

cardiotonic; sedative; diuretic