Pharmacognosy

DEPARTMENT OF PHARMACOGNOSY AND BOTANY

MPM, containing coumarins and chromones

Plants for practical course*

 

MPM name

Source

Constituents

Action, use

Fructus Visnagae daucoides (Fructus Ammi visnagae)

Visnaga daucoides (Ammi visnaga Lam.), (khella), Apiaceae

furanochromones (2-4%), including khellin,visnagin , angular pyrano-coumarins (visnadin); lipids (up to 18%), furanoacetophenones, flavonoids, essential oil

khellin is a spasmolytic agent; visnadin is a coronary vasodilator and a positive inotropic, bradycardic, and spasmolytic agent

Folia Ficusi caricae, Fructus Ficusi caricae

Ficus Carica Linn (fig), Moraceae

polysaccharides; mucilages; fat; proteins; pectins; organic acids; vitamins in fruits. Leaves contain phurocoumarins (psoralen, angelicine, bergaptene); tannins; volatile oils.

laxative and food; photosynthesizing due to psoralen and bergaptene

Fructus Anethi graveolentis

Anethum graveolens L. (Peucedanum graveolens Benth. and Hooker filius)(dill), Apiaceae

phuranochromones (visnagine and khellin), pyranocoumarins (visnadine); flavonoids; volatile and fixed oils

coronary spasmolytic; diuretic and aromatic, carminative and stimulant in gastro-intestinal diseases

 

Fructus Psoraleae

Psoralea drupacea, Fabaceae

phurocoumarins psoralen, umbelliferone

psoralens are photosensitizing agents in vitiligo treatment

Fructus Ammi majoris

Ammi majus, Apiaceae

methoxilied psoralen derivatives-bergaptene, xanthotoxin

photosensitizing agent in vitiligo treatment and for symptomatic control of psoriasis

Fructus Pastinacae sativae

Pastinaca sativa, Apiaceae

imperatorine, bergaptene, xanthotoxin; volatile oils

photosensitizing and spasmolytic

Radices Angelicae

Angelica archangelica L. (Archangelica officinalis Hoffm.), (angelica), Apiaceae

 

coumarins: simple, furanoid and hydroxyisopropylfuranoid, linear and angular (osthol, bergapten, xanthotoxin, angelicin, archangelicin), imperatorin, angelic acid; essential oil; organic and fatty acids; flavonoids

aromatic bitter; decoction is spasmolytic, anti-iflammatory and sedative, tincture is used in neuralgias and radiculitis. Fruits are used orally to treat the symptoms of gastrointestinal disturbances (bloating, eructations, flatulence)

Semina Hippocastani,

Folia Hippocastani

Aesculus hippocastanum L (common horse chestnut),

Hippocastanaceae

 

aesculin and fraxine; starch (40-50%); lipids (6-8%), flavonol glycosides, cyclitols, and saponins (aescine)

aescin is antiedema agent treats the symptoms of venous and lymphatic vessel insufficiency

Herba Meliloti

Melilotus officinalis (L.) Pall. (sweet clower), Fabaceae

melilotoside; saponins with a pentacyclic triterpenoid aglycone, flavonoids, and about 15 phenolic acids

venous and lymphatic vessels disorders, including itching, fullness in the legs, nocturnal cramps, edema, post-thrombotic syndrome, lymphatic congestion, and hemorrhoids; topically for contusions, sprains, or superficial bleeding